Hello, I'm
Răzvan V. Chereji
Quantitative Finance Researcher | Former Physicist & Computational Biologist
About Me
After earning my PhD in statistical mechanics/biophysics and completing a postdoctoral fellowship in computational biology, I seized the opportunity to explore new challenges and chart a new career direction. Motivated by a passion for continuous learning and personal growth, I transitioned into quantitative finance in October 2019, relocating to Princeton to pursue research in this dynamic field.
Publications
Peer-reviewed articles and book chapters
Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast
Qiu, H., Biernat, E., Govind, C. K., Rawal, Y., Chereji, R.V., Clark, D. J., Hinnebusch, A.G.
Nucleic Acids Res. 48(15), 8408-8430 (2020)
10.1093/nar/gkaa571Creating 2D occupancy plots using plot2DO
Beati, P., Chereji, R.V.
Stem Cell Transcriptional Networks 93-108 (2020)
10.1007/978-1-0716-0301-7_5Differential nucleosome spacing in neurons and glia
Clark, S., Chereji, R.V., Lee, P., Fields, R.D., Clark, D.J.
Neurosci Lett. 134559 (2019)
10.1016/j.neulet.2019.134559Quantitative MNase-seq accurately maps nucleosome occupancy levels
Chereji, R.V., Bryson, T.D., Henikoff, S.
Genome Biol. 20(1), 1-18 (2019)
10.1186/s13059-019-1815-zAccessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation
Chereji, R.V.*, Eriksson, P.R.*, Ocampo, J.*, Prajapati, H.K., Clark D.J.
Genome Res. gr-249326 (2019)
10.1101/gr.249326.119Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination
Ocampo, J.*, Chereji, R.V.*, Eriksson, P.R., Clark, D.J.
Genome Res. 29, 407–417 (2019)
10.1101/gr.242032.118Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects
Hamdani, O., Dhillon, N., Hsieh, T.-H.S., Fujita, T., Ocampo, J., Kirkland, J.G., Lawrimore, J., Kobayashi, T.J., Friedman, B., Fulton, D., Wu, K.Y., Chereji, R.V., Oki, M., Bloom, K., Clark, D.J., Rando, O.J., Kamakaka, R.T.
Mol. Cell Biol. (2019)
10.1128/MCB.00432-18Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins
Chang, H.-W., Valieva, M.E., Safina, A., Chereji, R.V., Wang, J., Kulaeva, O.I., Morozov, A.V., Kirpichnikov, M.P., Feofanov, A.V., Gurova, K.V., Studitsky, V.M.
Science Advances 4, eaav2131 (2018)
10.1126/sciadv.aav2131Single-Molecule Analysis Reveals Linked Cycles of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast
Mehta, G.D., Ball, D.A., Eriksson, P.R., Chereji, R.V., Clark, D.J., McNally, J.G., Karpova, T.S.
Mol. Cell 72, 875-887.e9 (2018)
10.1016/j.molcel.2018.09.009SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast
Rawal, Y.*, Chereji, R.V.*, Qiu, H., Ananthakrishnan, S., Govind, C.K., Clark, D.J., Hinnebusch, A.G.
Genes Dev. 32, 695–710 (2018)
10.1101/gad.312850.118SPT6 interacts with NSD2 and facilitates interferon-induced transcription
Ouda, R., Sarai, N., Nehru, V., Patel, M.C., Debrosse, M., Bachu, M., Chereji, R.V., Eriksson, P.R., Clark, D.J., Ozato, K.
FEBS Letters 592, 1681–1692 (2018)
10.1002/1873-3468.13069Major Determinants of Nucleosome Positioning
Chereji, R.V., Clark, D.J.
Biophys. J. 114, 2279–2289 (2018)
10.1016/j.bpj.2018.03.015Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast
Rawal, Y.*, Chereji, R.V.*, Valabhoju, V., Qiu, H., Ocampo, J., Clark, D.J., Hinnebusch, A.G.
Molecular Cell 70, 297-311.e4 (2018)
10.1016/j.molcel.2018.03.007Precise genome-wide mapping of single nucleosomes and linkers in vivo
Chereji, R.V.*, Ramachandran, S.*, Bryson, T.D., Henikoff, S.
Genome Biol. 19, 19 (2018)
10.1186/s13059-018-1398-0Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo
Johnson, T.A.*, Chereji, R.V.*, Stavreva, D.A., Morris, S.A., Hager, G.L., Clark, D.J.
Nucleic Acids Res. 46, 203–214 (2018)
10.1093/nar/gkx1044Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly
Chereji, R.V.*, Bharatula, V.*, Elfving, N., Blomberg, J., Larsson, M., Morozov, A.V., Broach, J.R., Björklund, S.
Nucleic Acids Res. 45, 8806–8821 (2017)
10.1093/nar/gkx491MNase-Sensitive Complexes in Yeast: Nucleosomes and Non-histone Barriers
Chereji, R.V.*, Ocampo, J.*, Clark, D.J.
Mol. Cell 65, 565-577.e3 (2017)
10.1016/j.molcel.2016.12.009The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo
Ocampo, J.*, Chereji, R.V.*, Eriksson, P.R., Clark, D.J.
Nucleic Acids Res. 44, 4625–4635 (2016)
10.1093/nar/gkw068Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation
Qiu, H.*, Chereji, R.V.*, Hu, C., Cole, H.A., Rawal, Y., Clark, D.J., Hinnebusch, A.G.
Genome Res. 26, 211–225 (2016)
10.1101/gr.196337.115Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster
Chereji, R.V.*, Kan, T.-W.*, Grudniewska, M.K., Romashchenko, A.V., Berezikov, E., Zhimulev, I.F., Guryev, V., Morozov, A.V., Moshkin, Y.M.
Nucleic Acids Res. 44, 1036–1051 (2016)
10.1093/nar/gkv978Functional roles of nucleosome stability and dynamics
Chereji, R.V., Morozov, A.V.
Brief. Funct. Genomics 14, 50–60 (2015)
10.1093/bfgp/elu038Heavy transcription of yeast genes correlates with differential loss of histone H2B relative to H4 and queued RNA polymerases
Cole, H.A., Ocampo, J., Iben, J.R., Chereji, R.V., Clark, D.J.
Nucleic Acids Res. 42, 12512–12522 (2014)
10.1093/nar/gku1013RSC-dependent constructive and destructive interference between opposing arrays of phased nucleosomes in yeast
Ganguli, D.*, Chereji, R.V.*, Iben, J.R., Cole, H.A., Clark, D.J.
Genome Res. 24, 1637–1649 (2014)
10.1101/gr.177014.114Ubiquitous nucleosome crowding in the yeast genome
Chereji, R.V., Morozov, A.V.
Proc. Natl. Acad. Sci. USA 111, 5236–5241 (2014)
10.1073/pnas.1321001111A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress
Elfving, N.*, Chereji, R.V.*, Bharatula, V., Björklund, S., Morozov, A.V., Broach, J.R.
Nucleic Acids Res. 42, 5468–5482 (2014)
10.1093/nar/gku176Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses
Petrenko, N., Chereji, R.V., McClean, M.N., Morozov, A.V., Broach, J.R.
Mol. Biol. Cell 24, 2045–2057 (2013)
10.1091/mbc.e12-12-0870Statistical Mechanics of Nucleosomes Constrained by Higher-Order Chromatin Structure
Chereji, R.V., Morozov, A.V.
J. Stat. Phys. 144, 379–404 (2011)
10.1007/s10955-011-0214-yStatistical mechanics of nucleosome ordering by chromatin-structure-induced two-body interactions
Chereji, R.V., Tolkunov, D., Locke, G., Morozov, A.V.
Phys. Rev. E 83, 050903 (2011)
10.1103/PhysRevE.83.050903* These authors contributed equally
Curriculum Vitae
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